CHARLES RIVER LABORATORIES, INC.

Class 009: Downloadable software for microbial data analytics, data and instrument management, instrument control, investigation analysis, process monitoring, quality control testing, environmental monitoring, predictive analytics, machine learning, and general analytics, specifically designed for microbial data analysis in the pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; downloadable software for detecting, recording, and analyzing contaminants to enhance quality control testing in the pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; downloadable software for quality control testing of data and facilitating scalability and adaptability to future technological advancements and regulatory requirements in microbial data analysis in the pharmaceutical products, nonsterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries.; Class 042: Non-downloadable software for microbial data analytics, data and instrument management, instrument control, investigation analysis, process monitoring, quality control testing, environmental monitoring, predictive analytics, machine learning, and general analytics, specifically designed for microbial data analysis in the pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; non-downloadable software for detecting, recording and analyzing contaminants to enhance quality control testing in pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; non-downloadable software for handling quality control testing data and facilitating scalability and adaptability to future technological advancements and regulatory requirements in microbial data analysis in the pharmaceutical products, nonsterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries.

Class 009: Downloadable software for microbial data analytics, data and instrument management, instrument control, investigation analysis, process monitoring, quality control testing, environmental monitoring, predictive analytics, machine learning, and general analytics, specifically designed for microbial data analysis in the pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; downloadable software for detecting, recording, and analyzing contaminants to enhance quality control testing in the pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; downloadable software for quality control testing of data and facilitating scalability and adaptability to future technological advancements and regulatory requirements in microbial data analysis in the pharmaceutical products, nonsterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries.; Class 042: Non-downloadable software for microbial data analytics, data and instrument management, instrument control, investigation analysis, process monitoring, quality control testing, environmental monitoring, predictive analytics, machine learning, and general analytics, specifically designed for microbial data analysis in the pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; non-downloadable software for detecting, recording and analyzing contaminants to enhance quality control testing in pharmaceutical products, non-sterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries; non-downloadable software for handling quality control testing data and facilitating scalability and adaptability to future technological advancements and regulatory requirements in microbial data analysis in the pharmaceutical products, nonsterile products, biologics, advanced therapy medicinal products (ATMP), personal care products, and cosmetics manufacturing industries.

Class 035: Lobbying services for commercial purposes, including promoting awareness of and interest in alternatives to animal testing; Class 036: Providing grants for research in animal testing alternatives; Providing scholarships for research in animal testing alternatives; financial services, namely, funding research awards in the field of advancing alternatives to animal testing; Class 041: Arranging and conducting symposia and conferences in the field of animal testing and alternatives therefor; publishing, namely, publishing and electronic online publishing of newsletters, white papers, and pamphlets in the field of animal testing and alternatives therefor; publishing and electronic online publishing of results of studies regarding the nature and extent of animal testing and regarding animal testing alternatives; publishing and electronic online publishing of the results of surveys of opinions among the public, industries, and government related to animal testing and alternatives therefor; Class 042: Research and development in the field of animal testing and alternatives therefor, animal-free drug alternatives, and animal-free alternatives for human medical test components; Class 045: Political lobbying services in the field of promoting the interests of animals and supporters of animal welfare and promoting alternatives to animal testing in legislation and regulation

Arranging and conducting symposia and conferences in the field of animal testing and alternatives therefor; publishing, namely, publishing and electronic online publishing of newsletters, white papers, and pamphlets in the field of animal testing and alternatives therefor; publishing and electronic online publishing of results of studies regarding the nature and extent of animal testing and regarding animal testing alternatives; publishing and electronic online publishing of the results of surveys of opinions among the public, industries, and government related to animal testing and alternatives therefor; Providing grants for research in animal testing alternatives; Providing scholarships for research in animal testing alternatives; financial services, namely, funding research awards in the field of advancing alternatives to animal testing; Promoting awareness of animal welfare, alternatives to animal testing, animal-free drug alternatives, and animal-free alternatives for human medical test components; lobbying services for commercial purposes, including promoting awareness of and interest in alternatives to animal testing; conducting public opinion surveys in the field of animal testing and alternatives therefor among the public, industries, and government; Promoting the interests of animals and supporters of animal welfare and promoting alternatives to animal testing in the fields of legislation and regulation; promoting collaboration within the scientific, research, drug manufacturing, and medical test manufacturing communities to achieve advances in the field of animal testing alternatives; Political lobbying services in the field of promoting the interests of animals and supporters of animal welfare and promoting alternatives to animal testing in legislation and regulation; Research and development in the field of animal testing and alternatives therefor, animal-free drug alternatives, and animal-free alternatives for human medical test components

Arranging and conducting symposia and conferences in the field of animal testing and alternatives therefor; publishing, namely, publishing and electronic online publishing of newsletters, white papers, and pamphlets in the field of animal testing and alternatives therefor; publishing and electronic online publishing of results of studies regarding the nature and extent of animal testing and regarding animal testing alternatives; publishing and electronic online publishing of the results of surveys of opinions among the public, industries, and government related to animal testing and alternatives therefor; Providing grants for research in animal testing alternatives; providing scholarships for research in animal testing alternatives; financial services, namely, funding research awards in the field of advancing alternatives to animal testing; Promoting awareness of animal welfare, alternatives to animal testing, animal-free drug alternatives, and animal-free alternatives for human medical test components; Commercial lobbying services in the field of animal welfare; public opinion polling regarding animal testing and alternatives therefor among the public, industries, and government; promoting collaboration within the scientific, research, drug manufacturing, and medical test manufacturing communities to achieve advances in the field of animal testing alternatives; Political lobbying services in the field of promoting the interests of animals and supporters of animal welfare and promoting alternatives to animal testing in legislation and regulation

Testing, inspection, research, or development of pharmaceutical preparations for gene therapy; Design, development, and testing services for others in the fields of biotechnology and biopharmaceutical research; Biological testing services in the field of drug development and manufacturing; scientific testing services, namely, quality control of pharmaceutical preparations for gene and cell therapy, biologics, chemical reagents, biochemical assays, biotechnology, and biopharmaceuticals.

Testing, inspection, research, or development of pharmaceutical preparations for gene therapy; Design, development, and testing services for others in the fields of biotechnology and biopharmaceutical research; Biological testing services in the field of drug development and manufacturing; scientific testing services, namely, quality control of pharmaceutical preparations for gene and cell therapy, biologics, chemical reagents, biochemical assays, biotechnology, and biopharmaceuticals.

Scientific and technological services, namely, scientific research in the field of medicine and pharmaceuticals; scientific and technological services, namely, testing and analysis of medicine and pharmaceuticals; scientific and technological services, namely, research and development of technology in the field of medicine and pharmaceuticals; research and development and consultation related thereto in the field of antibody development; scientific research services, namely, antibody engineering for analytical and clinical purposes; antibody engineering; custom design and engineering of antibodies; research in the field of antibodies, using a platform of biological research tools and techniques; providing an online database containing antibody information for research purposes

Research and development services in the field of viral vector development for use in laboratory, scientific, and clinical settings

Assays for scientific and research use; Reagents for scientific and research use; Assays, chemicals, reagents, and excipients for use in non-medical testing purposes, namely, bacterial endotoxin testing; Biochemicals for scientific use, namely, bacterial endotoxin testing; Custom design and development of biochemical assays; Laboratory research, namely, custom assay development for use in bacterial endotoxin testing

Assays for research purposes | Drug discovery services; Custom design and development of chemical reagents and biochemical assays; Providing laboratory research services in the field of pharmaceutical drug development and discovery via assay development, high-throughput screenings, small molecule compound libraries, peptide substrate profiling, and affinity selection mass spectrometry (ASMS)

Cell microarray screening and bioanalytical services for scientific and medical research purposes; Providing target screening analysis of plasma membrane, intracellular proteins, secreted proteins, protein complexes and associated post-translational modifications by using novel cell-based technologies; Drug discovery services; Pharmaceutical drug development and discovery services, namely, providing a DNA-encoded protein library screening for test articles; Scientific research services, namely, identification of cell surface receptors, specificity and off-target testing, target deconvolution and functionality assessment, for small molecules, large molecules, antibodies and related molecules, proteins, and cell and gene therapies

Laboratory equipment, namely, colony counters, plate racks, petri dish carriers, and petri dishes; Colony counters for laboratory use; Benchtop systems comprised of colony counter instruments and associated downloadable software for enumerating microbial colonies; Benchtop systems comprised of computer hardware designed to enumerate microbial colonies; Downloadable computer software for enumerating microbial colonies via image recognition and machine learning; Downloadable cloud-based computer software for enumerating microbial colonies via image recognition and machine learning; Platform as a service (PAAS) featuring computer software platforms for microbial colony counting; Software as a service (SAAS) services featuring software for microbial colony counting; Providing temporary use of non-downloadable, browser-based software for enumerating microbial colonies via image recognition and machine learning

Cells for scientific and research use; Cells for scientific, laboratory or medical research; Stem cells for research purposes; Biological tissue, namely, blood, stem cells, umbilical cords and placentas for scientific and medical research use; Biological tissue, namely, bone marrow, cord blood, normal peripheral blood, and mobilized peripheral blood, for use in scientific and medical research; Stem cells for research or scientific purposes; Biological tissue, namely, blood for scientific or medical research use

Platform as a service (PAAS) featuring computer software platforms for animal colony management; Software as a service (SAAS) services featuring software for animal colony management

"TEAR"; Containers, not of metal for commercial use; Containers for transport, not of metal; Nonmetal containers for use in transport of live animals for commercial or industrial use; Nonmetal containers for use in transport of live animals for scientific purposes

Research and development services in the field of plasmid DNA for use in laboratory, scientific, and clinical settings

Research and development services in the field of viral vector development for use in laboratory, scientific, and clinical settings

Custom design and development of host cell protein assays

Contract manufacturing in the field of pharmaceuticals | Drug discovery services

Biological tissue, namely, bone marrow, cord blood, normal peripheral blood, and mobilized peripheral blood, for use in scientific and medical research; Cells for scientific and research use; Cells for scientific, laboratory or medical research; Stem cells for research purposes; Biological tissue, namely, blood, stem cells, umbilical cords and placentas for scientific and medical research use; Stem cells for research or scientific purposes; Biological tissue, namely, blood for scientific or medical research use | Cells for medical or clinical use; Solutions for medical and clinical use in storing and treating cells, blood and blood components; Stem cells for medical or veterinary use; Stem cells for medical purposes

Scientific laboratory services; Laboratory analysis in the field of bacteriology, virology, and microbiology; Laboratory services, namely, screening and detection of microorganisms

Pharmaceutical drug development services; Pharmaceutical drug development services via software using artificial intelligence; Pharmaceutical drug development services via software using machine learning; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds via software using artificial intelligence; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds via software using machine learning; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery via software using artificial intelligence; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery via software using machine learning; Pharmaceutical drug development and discovery services, namely, identifying, designing, optimizing, and developing chemical lead series or lead compounds via software using artificial intelligence, machine learning, computational modeling, DNA-encoded library screening platform, high-throughput screening, medicinal chemistry, ADME, biology, pharmacology and/or non-GLP safety testing

Pharmaceutical drug development services; Pharmaceutical drug development services via software using artificial intelligence; Pharmaceutical drug development services via software using machine learning; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds via software using artificial intelligence; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds via software using machine learning; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery via software using artificial intelligence; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery via software using machine learning; Pharmaceutical drug development and discovery services, namely, identifying, designing, optimizing, and developing chemical lead series or lead compounds via software using artificial intelligence, machine learning, computational modeling, DNA-encoded library screening platform, high-throughput screening, medicinal chemistry, ADME, biology, pharmacology and/or non-GLP safety testing

Pharmaceutical drug development services; Pharmaceutical drug development services via software using artificial intelligence; Pharmaceutical drug development services via software using machine learning; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds via software using artificial intelligence; Preclinical drug discovery and development services used for identifying, designing and/or optimizing chemical compounds via software using machine learning; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery via software using artificial intelligence; Pharmaceutical evaluation and preclinical evaluation of chemical series or lead compounds in drug discovery via software using machine learning; Pharmaceutical drug development and discovery services, namely, identifying, designing, optimizing, and developing chemical lead series or lead compounds via software using artificial intelligence, machine learning, computational modeling, DNA-encoded library screening platform, high-throughput screening, medicinal chemistry, ADME, biology, pharmacology and/or non-GLP safety testing

Software as a service (SAAS) featuring software for providing key characteristics about specific microorganisms; Providing an on-line database in the field of microbiology for scientific research purposes

Platform as a service (PAAS) featuring an online computer software ecommerce platform used for connecting customers in any scientific discipline, allowing customers to obtain data and place orders for scientific research and facilitating communication with individual experts, academic core facilities, government labs and for-profit companies, and enabling online discussions and social networking; Design and development of on-line computer software systems, namely, design and development of an online data sharing, procurement and social networking and communications platform for scientists and research suppliers to share information, create custom studies, get price quotes, establish legal agreements and purchase research services and custom products; Platform as a service (PAAS) featuring an online social networking and communications software platform used to enable communication with potential customers, the exchange of information and selling of custom research services and products; Platform as a service (PAAS) featuring an online computer software platform used to manage both internal and external research sourcing projects and used for sharing of scientific information and institutional knowledge across a research organization through a central hub

assays, chemicals and reagents for use in non-medical testing purposes, namely, for use in an optimized recombinant technology for bacterial endotoxin testing; biochemicals, namely, an optimized recombinant technology for bacterial endotoxin testing for scientific use; chemical, biochemical, and biological preparations for scientific, pharmaceutical, biological, medical, and biomedical research and development, and for laboratory animal diagnostic use for scientific and research purposes | laboratory apparatus for screening and analyzing samples, namely, a screening panel | laboratory research, namely, custom assay development for use in an optimized recombinant technology for bacterial endotoxin testing

Assays, chemicals and reagents for use in non-medical testing purposes, namely, for use in the detection of microorganisms in the quality assurance testing of raw goods, consumer products, and pharmaceutical products; chemicals used in industry and science; chemicals used for testing the presence or absence of microbial contamination in raw materials or finished products; chemical reagents for non-medical purposes; diagnostic preparations and substances for non-medical purposes; chemicals used in industry, namely, reconstitution buffers used to reconstitute chemical reagents; releasing agents, namely, agents for releasing Adenosine Triphosphate (ATP); biochemicals, namely, antibody dilution buffers for scientific use; distilled water, namely, depleted water that has been depleted of contaminants that may otherwise influence tests using chemical reagents; chemical additives for use in the manufacture of a wide variety of goods; chemicals used in industry, namely, reconstitution buffers used to reconstitute chemical reagents

Business consulting, management, and planning services in the field of corporate compliance and ethics programs, including but not limited to as outlined in §8B2.1 of the U.S. Federal Sentencing Guidelines for Organizations and/or which address compliance and ethics risk topics such as anti-bribery and anti-corruption, code of business conduct and ethics, compliance program effectiveness, conflicts of interest, gifts and entertainment, environment, health and safety, fair competition, financial integrity and fraud, government contracts and business relationships between government and government contractors, harassment and discrimination, hotline and reporting, insider trading and dealing related to the recording and registering of the transfer of securities and related securities disclosure laws, intellectual properties, international trade compliance, investigations, privacy and data protection, records management and retention, and social media

Scientific apparatus, namely, assay kits consisting of reagents, vials and buffers for scientific research use in the detection of microorganisms | Scientific apparatus and instruments, namely, luminometers for use in the detection of microorganisms

ANIMAL HUSBANDRY; PROVIDING VIVARIUMS WITH STAFF ENGAGING HUSBANDRY, namely providing breeding services for laboratory animals; PROVIDING AN VIVARIUM RENTAL SPACE, namely, rental of facilities for breeding and housing laboratory animals

Consulting services in the fields of laboratory testing and environmental testing; Laboratory analysis in the field of comparative DNA sequencing, microbiology, protein analysis, serology, microbiology and parasitology; environmental testing and inspection services; environmental testing, namely, laboratory exhaust testing; Environmental monitoring, namely, environmental testing and inspection services; Technical consulting in the field of the detection of bacteria and pathogens for scientific and medical research purposes; Medical research consultation services in the field of the detection of bacteria and pathogens for scientific and medical research purposes; Scientific consultation services in the field of the detection of bacteria and pathogens for scientific and medical research purposes

Consulting services for others in the field of design, planning, and implementation project management of medical laboratories and clinical trials

Laboratory analysis in the field of comparative DNA sequencing, microbiology, protein analysis, serology, microbiology and parasitology; Research and development and consultation related thereto in the field of biotechnology, pharmaceutical research and development, laboratory testing, diagnostics, and pharmacogenetics

Consulting services in the fields of biotechnology, pharmaceutical research and development, laboratory testing, and pharmacogenetics; Laboratory analysis in the field of comparative DNA sequencing, microbiology, protein analysis, serology, microbiology and parasitology

Laboratory apparatus for screening and analyzing samples, namely, a screening panel; a plate for performing phase reactions and screening and analyzing samples; a plate for enabling high throughput sample preparation and presentation; a plate for screening and analyzing molecular arrays that enables high throughput sample preparation and presentation

Class 035: Data management services and database management services for use with genetic testing, genetic research, animal research and studies, health surveillance programs, and medical research

Consulting in the field of business management for laboratories and clinical trials; consulting in the field of employment recruiting for clinical trials; business and office support staff services for laboratories and clinical trials

Cardboard containers

Live laboratory animals

Live laboratory animals

"DEDICATED RESOURCES"

genetic testing of laboratory animals for research purposes | Genetic testing of laboratory animals for medical purposes; breeding of congenic laboratory animals; genetic testing of animals; animal breeding

"MOUSE"

Live laboratory animals, namely, mice

Class 042: Laboratory research services, namely diagnostic testing services for laboratory animals; research and product development; and research and development for new products for others

Class 001: Chemical, biochemical, and biological preparations for scientific, pharmaceutical, biological, medical, and biomedical research and development, and for laboratory animal diagnostic use for scientific and research purposes

Class 042: Laboratory research services, namely diagnostic testing services for laboratory animals; research and product development; and research and development for new products for others

spectrophotometers; computer software for the acquisition, analysis, and creation of databases of scientific, pharmaceutical, biological, medical, and biomedical data; downloadable electronic publications in the nature of brochures, newsletters, data sheets, technical papers, and abstracts in the fields of science and technology

providing contract, temporary, and permanent personnel staffing services; personnel management and consultancy services; human resources management; recruiting, training, and managing the provision of temporary contract personnel; providing information and consultancy services on the procurement of temporary, contract, and permanent personnel; serving as a human resource department for others; employment outplacement services

Class 035: Providing contract, temporary, and permanent personnel staffing services; personnel management and consultancy services; human resources management; recruiting and managing the provision of temporary contract personnel; providing information and consultancy services on the procurement of temporary, contract, and permanent personnel; serving as a human resource department for others; employment outplacement service; Class 041: Training temporary contract personnel

spectrophotometers; computer software for the acquisition, analysis, and creation of databases of scientific, pharmaceutical, biological, medical, and biomedical data; downloadable electronic publications in the nature of brochures, newsletters, data sheets, technical papers, and abstracts in the fields of science and technology

publications in the nature of brochures, newsletters, data sheets, technical papers, and abstracts in the fields of science and technology

"LABORATORIES"